A defined barley seed extract with human-like growth factor activity, developed and produced for skincare and hair growth application

DERMOkine® is a portfolio of human growth factors in defined barley seed extract, developed and produced for skincare and hair growth application. The products contain high-quality, endotoxin-free, replicas of human growth factors and biopeptides, produced in the endosperm tissue of the barley plant (Hordeum vulgare).

The DERMOkine® portfolio is based on bioengineered, plant-based replicas of naturally occurring human growth factors and biopeptides and a broad range of barley seed proteins. These signalling peptides play a crucial role in maintaining the skin's natural youthfulness and vitality in response to both intrinsic and extrinsic factors.

Understanding what affects skin cells' performance and the components essential to their healthy function is key. Signalling peptides such as growth factors and biopeptides are essential in regulating and maintaining healthy skin and hair growth. As we age, the production of these peptides decreases, leading to slower cell regeneration, transformation and repair, which eventually affects skin appearance and hair growth.

DERMOkine success in the BIOEFFECT skincare:

ORF Genetics developed the award-winning premium skincare brand BIOEFFECT following its scientists’ discovery of the method to produce the EGF replica in bioengineered barley seeds. Using DERMOkine, BIOEFFECT became the first skincare brand in the world with plant-based human growth factor replicas and has since become a global success.

1

Experience & Trust

With over 18 years of experience supplying growth-factor and biopeptide solutions to the cosmetics industry, we combine scientific excellence with a deep understanding of commercial and formulation needs.

2

Plant-based Production

Our growth factors and biopeptides are produced in the barley (Hordeum vulgare) plant using our proprietary expression system — bypassing E. coli and mammalian cell contaminants, ensuring a pure, safe, and sustainable source.

3

Innovative & Diverse Portfolio

We offer an expanding portfolio of highly functional growth factors and biopeptides — including biomolecules that were previously beyond the cosmetic industry’s reach due to cost or scalability limitations.

4

Highly Scalable & Flexible Manufacturing

Our unique plant-based production platform is inherently scalable and adaptable — from early development to full commercial volumes, we grow with your needs.