IGF-1, LR3
€25 per 10μg
€50 per 50μg
€70 per 100μg
€200 per 1000μg
€300 per 2000μg
€775 per 5000μg
IK0300
Description
The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function but have a much higher growth-promoting activity than insulin. IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension. Specifically engineered for higher biological potency in vitro, IGF-I LR3 has an increased half-life and a binding aversion to native proteins within the body that make it ideal for both research and large-scale culturing.
Source
Produced in the endosperm tissue of barley grain (Hordeum vulgare).
Formulation
PBS pH 7.2, sterile filtered through 0.2 µm filter
Purity
Greater than 95% by SDS-PAGE gel analysis.
Reconstitution
Note: Always centrifuge the vial before opening. It is recommended to reconstitute the lyophilized protein in sterile buffered saline to a concentration of no less than 100 µg/ml. For long term storage of the recon statute solution it is recommended to add a carrier protein (0.1% HSA or BSA).
Stability
The lyophilized protein, though stable at room temperature for few weeks, is best stored at -20°C. Reconstituted protein should be used immediately or stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Biological Activity
Each batch of ISOkine growth factor is tested for bioactivity and verified to have comparable activity to a commercial source.
Endotoxin Level
Endotoxin level is less than 0.005ng per µg of ISOkine product (0.05EU/µg).