Publications & Citations

Greggi, C.; Montanaro, M.; Scioli, M.G.; Puzzuoli, M.; Gino Grillo, S.; Scimeca, M.; Mauriello, A.; Orlandi, A.; Gasbarra, E.; Iundusi, R.; et al. Modulation of Carnitine Palmitoyl Transferase 1b Expression and Activity in Muscle Pathophysiology in Osteoarthritis and Osteoporosis. Biomolecules 2024, 14, 1289. https://doi.org/10.3390/biom14101289

Bodiou V, Kumar AA, Massarelli E, van Haaften T, Post MJ and Moutsatsou P (2024) Attachment promoting compounds significantly enhance cell proliferation and purity of bovine satellite cells grown on microcarriers in the absence of serum. Front. Bioeng. Biotechnol. 12:1443914. doi: 10.3389/fbioe.2024.1443914

Pekec, T., Lewandowski, J., Komur, A.A. et al. Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons. Nat Commun 13, 4883 (2022). https://doi.org/10.1038/s41467-022-32500-z

D’Agostino S, Tombolan L, Saggioro M, Frasson C, Rampazzo E, Pellegrini S, Favaretto F, Biz C, Ruggieri P, Gamba P, Bonvini P, Aveic S, Giovannoni R and Pozzobon M (2021) Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study. Front. Oncol. 10:600980. doi: 10.3389/fonc.2020.600980

Martha Stokking, Marta Cadenas-Martín, Ana I Martín-González, Alba Fernández-Ferrer, Francisco Arnalich-Montiel, Maria P De Miguel. Three-dimensional-printed collagen scaffold with limbal stem cells derived from adipose-derived mesenchymal stem cells for the treatment of limbal stem cell deficiency. International Journal of Bioprinting, 2025, 11(6): 407-429 DOI:10.36922/IJB025290293

Cadenas-Martin, M.; Arnalich-Montiel, F.; Miguel, M.P.D. Derivation of Limbal Stem Cells from Human Adult Mesenchymal Stem Cells for the Treatment of Limbal Stem Cell Deficiency. Int. J. Mol. Sci. 2023, 24, 2350. https://doi.org/10.3390/ijms24032350

Tavasoli, M., Lahire, S., Sokolenko, S. et al. Mechanism of action and therapeutic route for a muscular dystrophy caused by a genetic defect in lipid metabolism. Nat Commun 13, 1559 (2022). https://doi.org/10.1038/s41467-022-29270-z

Pekec, T., Lewandowski, J., Komur, A.A. et al. Ferritin-mediated iron detoxification promotes hypothermia survival in Caenorhabditis elegans and murine neurons. Nat Commun 13, 4883 (2022). https://doi.org/10.1038/s41467-022-32500-z

D’Agostino S, Tombolan L, Saggioro M, Frasson C, Rampazzo E, Pellegrini S, Favaretto F, Biz C, Ruggieri P, Gamba P, Bonvini P, Aveic S, Giovannoni R and Pozzobon M (2021) Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study. Front. Oncol. 10:600980. doi: 10.3389/fonc.2020.600980

Szojka ARA, Li DX, Sopcak MEJ, Ma Z, Kunze M, Mulet-Sierra A, Adeeb SM, Westover L, Jomha NM and Adesida AB (2021) Mechano-Hypoxia Conditioning of Engineered Human Meniscus. Front. Bioeng. Biotechnol. 9:739438. doi: 10.3389/fbioe.2021.739438

López-Iglesias P, Alcaina Y, Tapia N, et al. Hypoxia Induces Pluripotency in Primordial Germ Cells by HIF1α Stabilization and Oct4 Deregulation. Antioxidants & Redox Signaling. 2015 ;22(3):205-223. doi:10.1089/ars.2014.5871

Razmkhah F, Soleimani M, Mehrabani D, et al. Leukemia microvesicles affect healthy hematopoietic stem cells. Tumor Biology. 2017 ;39(2). doi:10.1177/1010428317692234

Sierra H. Root, Héctor L. Aguila; Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood. Blood Adv 2021; 5 (21): 4435–4446. doi: https://doi.org/10.1182/bloodadvances.2021004552

Sierra H. Root, Héctor L. Aguila; Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood. Blood Adv 2021; 5 (21): 4435–4446. doi: https://doi.org/10.1182/bloodadvances.2021004552

Vogiatzis, S.; Celestino, M.; Trevisan, M.; Magro, G.; Del Vecchio, C.; Erdengiz, D.; Palù, G.; Parolin, C.; Maguire-Zeiss, K.; Calistri, A. Lentiviral Vectors Expressing Chimeric NEDD4 Ubiquitin Ligases: An Innovative Approach for Interfering with Alpha-Synuclein Accumulation. Cells 2021, 10, 3256. https://doi.org/10.3390/cells10113256

Lisse, T.S., Sharma, M., Vishlaghi, N. et al. GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells. npj Regen Med 5, 13 (2020). https://doi.org/10.1038/s41536-020-0098-z

Cuomo F, Dell’Aversana C, Chioccarelli T, Porreca V, Manfrevola F, Papulino C, Carafa V, Benedetti R, Altucci L, Cobellis G and Cobellis G (2022) HIF3A Inhibition Triggers Browning of White Adipocytes via Metabolic Rewiring. Front. Cell Dev. Biol. 9:740203. doi: 10.3389/fcell.2021.740203

Cuomo, F., Coppola, A., Botti, C. et al. Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells. Sci Rep 8, 5842 (2018). https://doi.org/10.1038/s41598-018-24221-5

de Jong, E., Lim, A., Waterer, G. and Price, P. (2012), Monocyte-derived macrophages do not explain susceptibility to pulmonary non-tuberculous mycobacterial disease. Clin Trans Immunol, 1: e2. https://doi.org/10.1038/cti.2012.1

Appleby SJ, Misica‐Turner P, Oback FC, Dhali A, McLean ZL and Oback B (2022) Double cytoplast embryonic cloning improves in vitro but not in vivo development from mitotic pluripotent cells in cattle. Front. Genet. 13:933534. doi: 10.3389/fgene.2022.933534

Hosaka N, Kanda S, Shimono T, Nishiyama T. Induction of γδT cells from HSC-enriched BMCs co-cultured with iPSC-derived thymic epithelial cells. J Cell Mol Med. 2021 ;25:10604–10613. doi:10.1111/jcmm.16993

Jiang Z, Generoso SF, Badia M, Payer B, Carey LB (2021) A conserved expression signature predicts growth rate and reveals cell & lineage-specific differences. PLOS Computational Biology 17(11): e1009582. https://doi.org/10.1371/journal.pcbi.1009582

Yoshiteru Yano, Naoya Iimura, Nobuhiko Kojima, Hideho Uchiyama, Non-neural and cardiac differentiating properties of Tbx6-expressing mouse embryonic stem cells, Regenerative Therapy, Volume 3, 2016, Pages 1-6, ISSN 2352-3204, https://doi.org/10.1016/j.reth.2016.02.001.

Jaewoong Yoon, Wonju Jo, Dayeong Jeong, Junho Kim, Hwapyeong Jeong, Jaesung Park, Generation of nanovesicles with sliced cellular membrane fragments for exogenous material delivery, Biomaterials, Volume 59, 2015, https://doi.org/10.1016/j.biomaterials.2015.04.028

Adam C. Wilkinson, Debbie K. Goode, Yi-Han Cheng, Diane E. Dickel, Sam Foster, Tim Sendall, Marloes R. Tijssen, Maria-Jose Sanchez, Len A. Pennacchio, Aileen M. Kirkpatrick, Berthold Göttgens; Single site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses. Biol Open 15 November 2013; 2 (11): 1229–1238. doi: https://doi.org/10.1242/bio.20136296

Tavano, R., Morillas-Becerril, L., Geffner-Smith, A. et al. Species differences in opsonization and phagocyte recognition of preclinical poly-2-alkyl-2-oxazoline-coated nanoparticles. Nat Commun 16, 2642 (2025). https://doi.org/10.1038/s41467-025-57648-2

Quentin Glaziou, Laetitia Basset, Sènan d’Almeida, Pascale Pignon, Nabila Jabrane-Ferrat, Christophe Blanquart, Yves Delneste, Julie Tabiasco. IL-27 neutralization enhances macrophage polarization and improves immune checkpoint efficacy bioRxiv 2024.09.13.612803; doi: https://doi.org/10.1101/2024.09.13.612803

d’Almeida, S. M., Kauffenstein, G., Roy, C., Basset, L., Papargyris, L., Henrion, D., … Tabiasco, J. (2016). The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27. OncoImmunology, 5(7). https://doi.org/10.1080/2162402X.2016.1178025

de Jong, E., Lim, A., Waterer, G. and Price, P. (2012), Monocyte-derived macrophages do not explain susceptibility to pulmonary non-tuberculous mycobacterial disease. Clin Trans Immunol, 1: e2. https://doi.org/10.1038/cti.2012.1

Zhang, L., Xiao, K., Zhang, S. et al. SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT activation. Sci Rep 15, 4779 (2025). https://doi.org/10.1038/s41598-025-89477-0

Zhang S, Zhang L, Zhang D, et al. Four and a half LIM domains 2 (FHL2) attenuates tumorigenesis of gastrointestinal stromal tumors (GISTs) by negatively regulating KIT signaling. Mol Carcinogen. 2024; 63: 1334-1348. doi:10.1002/mc.23727

Li, S., Zhao, S., Liang, N. et al. SPRY4 inhibits and sensitizes the primary KIT mutants in gastrointestinal stromal tumors (GISTs) to imatinib. Gastric Cancer 26, 677–690 (2023). https://doi.org/10.1007/s10120-023-01402-4

Shaoting Zhang, Liangying Zhang, Zongying Jiang, Yue Guo, Hui Zhao, Jianmin Sun. Protein tyrosine phosphatase receptor type E (PTPRE) regulates the activation of wild-type KIT and KIT mutants differently, Biochemistry and Biophysics Reports, Volume 26, 100974 (2021). https://doi.org/10.1016/j.bbrep.2021.100974.

Sierra H. Root, Héctor L. Aguila; Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood. Blood Adv 2021; 5 (21): 4435–4446. doi: https://doi.org/10.1182/bloodadvances.2021004552

Riccetti S, Sinigaglia A, Desole G, Nowotny N, Trevisan M, Barzon L. Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells. Viruses. 2020 Aug 12;12(8):882. doi: 10.3390/v12080882. PMID: 32806715; PMCID: PMC7471976.

Zhu, G., Shi, J., Zhang, S. et al. Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib. Cell Biosci 10, 16 (2020). https://doi.org/10.1186/s13578-020-0377-9

Phung B, Sun J, Schepsky A, Steingrimsson E, Rönnstrand L (2011) C-KIT Signaling Depends on Microphthalmia-Associated Transcription Factor for Effects on Cell Proliferation. PLoS ONE 6(8): e24064. https://doi.org/10.1371/journal.pone.0024064

Phung B, Sun J, Schepsky A, Steingrimsson E, Rönnstrand L (2011) C-KIT Signaling Depends on Microphthalmia-Associated Transcription Factor for Effects on Cell Proliferation. PLoS ONE 6(8): e24064. https://doi.org/10.1371/journal.pone.0024064

Cuomo F, Dell’Aversana C, Chioccarelli T, Porreca V, Manfrevola F, Papulino C, Carafa V, Benedetti R, Altucci L, Cobellis G and Cobellis G (2022) HIF3A Inhibition Triggers Browning of White Adipocytes via Metabolic Rewiring. Front. Cell Dev. Biol. 9:740203. doi: 10.3389/fcell.2021.740203

Cuomo, F., Coppola, A., Botti, C. et al. Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells. Sci Rep 8, 5842 (2018). https://doi.org/10.1038/s41598-018-24221-5

Lampronti, Ilaria, Manzione, Maria Giulia, Sacchetti, Gianni, Ferrari, Davide, Spisani, Susanna, Bezzerri, Valentino, Finotti, Alessia, Borgatti, Monica, Dechecchi, Maria Cristina, Miolo, Giorgia, Marzaro, Giovanni, Cabrini, Giulio, Gambari, Roberto, Chilin, Adriana, Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells, Mediators of Inflammation, 2017, 2389487, 11 pages, 2017. https://doi.org/10.1155/2017/2389487

Kerr, M., Gomez, G., Ferguson, C. et al. Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis. Nat Commun 8, 14729 (2017). https://doi.org/10.1038/ncomms14729

Cuomo F, Dell’Aversana C, Chioccarelli T, Porreca V, Manfrevola F, Papulino C, Carafa V, Benedetti R, Altucci L, Cobellis G and Cobellis G (2022) HIF3A Inhibition Triggers Browning of White Adipocytes via Metabolic Rewiring. Front. Cell Dev. Biol. 9:740203. doi: 10.3389/fcell.2021.740203

D’Alessandro, R.; Refolo, M.G.; Iacovazzi, P.A.; Pesole, P.L.; Messa, C.; Carr, B.I. Ramucirumab and GSK1838705A Enhance the Inhibitory Effects of Low Concentration Sorafenib and Regorafenib Combination on HCC Cell Growth and Motility. Cancers 2019, 11, 787. https://doi.org/10.3390/cancers11060787

Cuomo, F., Coppola, A., Botti, C. et al. Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells. Sci Rep 8, 5842 (2018). https://doi.org/10.1038/s41598-018-24221-5

Sharma, D., Hamlet, S., Petcu, E. et al. The effect of bisphosphonates on the endothelial differentiation of mesenchymal stem cells. Sci Rep 6, 20580 (2016). https://doi.org/10.1038/srep20580

N.K. Binder, J. Evans, D.K. Gardner, L.A. Salamonsen, N.J. Hannan, Endometrial signals improve embryo outcome: functional role of vascular endothelial growth factor isoforms on embryo development and implantation in mice, Human Reproduction, Volume 29, Issue 10, 10 October 2014, Pages 2278–2286, https://doi.org/10.1093/humrep/deu211

Sordo-Bahamonde, C.; Lorenzo-Herrero, S.; González-Rodríguez, A.P.; Payer, Á.R.; González-García, E.; López-Soto, A.; Gonzalez, S. LAG-3 Blockade with Relatlimab (BMS-986016) Restores Anti-Leukemic Responses in Chronic Lymphocytic Leukemia. Cancers 2021, 13, 2112. https://doi.org/10.3390/cancers13092112

Sierra H. Root, Héctor L. Aguila; Novel population of human monocyte and osteoclast progenitors from pluripotent stem cells and peripheral blood. Blood Adv 2021; 5 (21): 4435–4446. doi: https://doi.org/10.1182/bloodadvances.2021004552

Cuomo, F., Coppola, A., Botti, C. et al. Pro-inflammatory cytokines activate hypoxia-inducible factor 3α via epigenetic changes in mesenchymal stromal/stem cells. Sci Rep 8, 5842 (2018). https://doi.org/10.1038/s41598-018-24221-5

Panting M, Holme IB, Björnsson JM, Zhong Y and Brinch-Pedersen H (2021) CRISPR/Cas9 and Transgene Verification of Gene Involvement in Unfolded Protein Response and Recombinant Protein Production in Barley Grain. Front. Plant Sci. 12:755788. doi: 10.3389/fpls.2021.755788

Panting M, Holme IB, Björnsson JM, Brinch-Pedersen H. Modulation of Barley (Hordeum vulgare L.) Grain Protein Sink-Source Relations Towards Human Epidermal Growth Factor Instead of B-hordein Storage Protein. Mol Biotechnol. 2021 Jan;63(1):13-23. doi: 10.1007/s12033-020-00279-3. Epub 2020 Oct 13. PMID: 33051823.

Moon, K.-B.; Park, J.-S.; Park, Y.-I.; Song, I.-J.; Lee, H.-J.; Cho, H.S.; Jeon, J.-H.; Kim, H.-S. Development of Systems for the Production of Plant-Derived Biopharmaceuticals. Plants 2020, 9, 30. https://doi.org/10.3390/plants9010030

Iyappan Gowtham and Ramalingam Sathishkumar (2019) Advances in Plant Based Biologics, Next Generation Biomanufacturing Technologies, Chapter 4pp 57-79, DOI: 10.1021/bk-2019-1329.ch004

Magnusdottir A, Vidarsson H, Björnsson JM, Örvar BL. Barley grains for the production of endotoxin-free growth factors. Trends Biotechnol. 2013 Oct;31(10):572-80. doi: 10.1016/j.tibtech.2013.06.002. Epub 2013 Jul 10. PMID: 23849675.

Erlendsson, L.S., Muench, M.O., Hellman, U., Hrafnkelsdóttir, S.M., Jonsson, A., Balmer, Y., Mäntylä, E. and Örvar, B.L. (2010), Barley as a green factory for the production of functional Flt3 ligand. Biotechnology Journal, 5: 163-171. https://doi.org/10.1002/biot.200900111