IL-6 - New for 2026

IL-6 is a multifunctional cytokine with an essential role in host defense by regulating immune and inflammatory responses. It is expressed by various cell types, including T cells, B cells, monocytes/macrophages, fibroblasts, and possibly tumor cells. IL-6 has diverse biological functions, stimulating B-cell differentiation and antibody production, synergizing with other factors in hematopoiesis and platelet production, inducing hepatic acute-phase protein expression, and regulating bone metabolism.

Recombinant human IL-6 has a molecular weight of 21.5kDa containing 185 amino acid residues.

Produced in the endosperm tissue of barley grain (Hordeum vulgare).

Each batch of ISOkine® growth factor is tested for bioactivity and verified to have comparable activity to a commercial source.

Greater than 95% by SDS-PAGE gel analysis.

Endotoxin level is < 0.0100 EU per μg of ISOkine® product.

Purified ISOkine® product carries no pyrogenic or pro-inflammatory contaminants, as assayed with monocyte activation test (MAT Assay) using Human 10-plex Cytokine Assay measuring IL-6, TNF-alpha and IL-1 beta induction.

Highly stable as supplied for a maximum of 5 years and a minimum of 12 months from date of receipt (check expiration date specific for each lot# on Certificate of Analysis)

The lyophilized protein, though stable at room temperature for few weeks, is best stored at -20°C. Reconstituted protein should be used immediately or stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.

Note: Always centrifuge the vial before opening. It is recommended to reconstitute the lyophilized protein in sterile buffered saline to a concentration of no less than 100 µg/ml. For long term storage of the recon statute solution it is recommended to add a carrier protein (0.1% HSA or BSA).

PBS pH 7.2, sterile filtered through 0.2 µm filter