For cultivated meat & seafood
Species-specific growth factors, built for scale
MESOkine® delivers animal-free bovine, porcine, and avian growth factors for cultivated meat and seafood production. Consistent quality, reliable supply, significantly lower cost.
Quote-based. No account needed. Worldwide distribution.
Trusted by teams scaling cultivated meat
The scale-up problem
Growth factors are the hardest part of scaling cultivated meat
Standard mammalian-expressed factors are affordable for research volumes. At production scale, they price most teams out of commercial viability. The cost structure has to change.
Serum-containing media and animal-component growth factors introduce contamination risk and complicate your regulatory path. Biorisk-free inputs are not optional at production scale.
Human and mouse growth factors dominate the catalog. Bovine, porcine, and avian factors -- the ones cultivated meat producers actually need -- are a thin, expensive, unreliable market segment.
What MESOkine® makes possible
Purpose-built for cultivated meat, from research to production
MESOkine® is ORF's dedicated growth-factor line for cultivated meat and seafood -- animal-free, species-specific, and designed for the cost structure production volumes demand.
Run the same MESOkine® factors at bench scale and at commercial volume. ORF's molecular-farming economics mean cost-per-dose drops as volume grows. The supply chain that works in your R&D lab is the same one that works at production scale.
Replace serum-containing media with MESOkine® animal-free, endotoxin-free growth factors. An endotoxin-free plant host means no serum carryover, no contaminating endogenous cytokines, no prions -- biorisk-free from the ground up.
Source bovine, porcine, and avian growth factors from a single supplier. FGF basic, IGF-1 LR3, PDGF-BB, VEGF, LIF, EGF, Transferrin, IL-6 -- all MESOkine® catalog, bioactivity verified by independent third-party bioassays against highly purified commercial references.
The MESOkine® catalog
Every factor your process needs, from a single source
MESOkine® covers the growth factors most used in cultivated meat and seafood -- bovine, porcine, and avian -- produced in an endotoxin-free plant host and bioactivity-verified against highly purified commercial references.
Proliferation factors
FGF basic bovine/porcine (MK0201) drives cellular proliferation and is the most widely used growth factor in cultivated-meat media. IGF-1 LR3 bovine/porcine (MK0301) is engineered for higher biological potency in vitro with an extended half-life for large-scale culturing. Both are bioactivity-verified with ED50 below 0.1 ng/ml for FGF basic and below 2 ng/ml for IGF-1 LR3.
Differentiation and vascularisation factors
VEGF bovine (MK0501) stimulates endothelial proliferation and angiogenesis, supporting vascularisation in 3D tissue constructs. PDGF-BB porcine (MK0401) promotes mesenchymal stem cell recruitment and differentiation. LIF bovine (MK0601) maintains pluripotency and supports early-stage differentiation control.
Support and media factors
Transferrin bovine (MK0701) is an iron transport protein and standard serum-replacement component in defined media. EGF porcine (MK0801) is widely used in porcine cell culture media. IL-6 bovine supports cell survival and immune modulation in complex culture systems. All produced in an endotoxin-free plant host.
From cell isolation to commercial scale
How MESOkine® fits your process
Identify your cells and species
Select your animal cell type -- bovine, porcine, avian, or seafood. Talk to our scientists about your specific cell line and culture conditions. We will confirm which MESOkine® factors are the right fit for your application.
Validate at bench scale
Request a quote for research quantities. Each MESOkine® batch ships with a certificate of analysis and a datasheet confirming bioactivity against highly purified commercial references. Most labs complete head-to-head validation within weeks.
Scale up with the same supply
Transition to larger quantities using the same MESOkine® catalog numbers. ORF has invested to scale production capacity 14x by 2027. Your process does not change -- the supply just scales with you.
Receive worldwide, order when you need it
Ordering is quote-based through ORF's worldwide distributor network. Datasheets and safety data sheets are available for every product. ISO 9001 certified supply chain.
Companies scaling cultivated meat trust MESOkine®
ORF's barley-grown growth factors allow cultivated-meat companies like Vow not only to grow but to rapidly scale up production to meet future-market demands.
Questions from cultivated meat teams
Common questions about species coverage, bioactivity, animal-free inputs, scale-up, and ordering.
Yes. The MESOkine® catalog includes bovine FGF basic, IGF-1 LR3, VEGF, LIF, Transferrin, and IL-6; porcine FGF basic, IGF-1 LR3, EGF, and PDGF-BB; and avian variants. Each factor is species-matched to the animal cell type you are culturing. Contact us if your species is not listed -- our team can advise on cross-reactivity or custom production options.
Each MESOkine® batch is tested for bioactivity and verified to have comparable activity to a corresponding commercial source of highly purified growth factor, using commercially accepted bioassays performed by independent research organizations. Results are reported in a certificate of analysis and datasheet for every batch. You can validate head-to-head in your own assay before committing to scale.
MESOkine® growth factors contain no animal-derived substances -- no serum carryover, no endogenous cytokines, no antibiotics, no prions, and no bacteria or viruses. They are produced in barley endosperm (an endotoxin-free plant host) and are biorisk-free for cell culture use. This matters for your regulatory path and for the integrity of your process as you move toward commercial production.
Yes. ORF invested to scale MESOkine® production capacity 14x by 2027. Orders are fulfilled through a worldwide distributor network on a quote basis; larger quantities are available on request. The same catalog numbers you use at bench scale are available at production volumes -- your process does not need to change as you scale. Contact us to discuss your projected volume and timeline.
MESOkine® growth factors are not yet cGMP validated, but ORF is actively building a GMP-compliant production facility. In the meantime, MESOkine® represents a significant improvement in safety over traditionally produced growth factors -- endotoxin-free, biorisk-free, and ISO 9001 certified. For teams with GMP requirements, contact us to discuss your timeline and we will update you as our GMP program progresses.
Quotes and sample requests are handled by email and through our worldwide distributor network. For MESOkine® bulk orders and quotes, contact info@orfgenetics.com. Sample requests can also be submitted to the same address. There is no online ordering or account required -- just contact us or submit the quote request form and our team will respond directly.
Get started
Your cultivated meat process deserves a supply chain that scales with it
MESOkine® animal-free growth factors are produced for cultivated meat at scale. Request a quote or talk to our scientists about your species, cell line, and volume.
ISO 9001 certified · supplying cultivated meat companies worldwide