Organoids
Consistent growth factors for reproducible organoid models
ISOkine® provides defined, animal-free, endotoxin-free growth factors for epithelial and stem-cell-derived organoids. Batch-consistent quality keeps your models reproducible.
ISO 9001 certified, 25 years of molecular farming
Trusted by research teams worldwide
The organoid challenge
Factor variability undermines reproducibility
Organoid formation and expansion depend on precise factor activity. Shifts in potency between lots change morphology and yield, and reproducibility suffers.
Serum and animal-component inputs introduce variables you cannot control, confounding organoid models and downstream readouts.
Organoid cultures run for weeks. A gap or a changed formulation mid-project forces re-validation of an established protocol.
Why ISOkine for organoids
Defined conditions you can standardize a protocol on
Tell us your application and we'll recommend the right factors.
Batch-to-batch reproducibility
Each ISOkine® lot is bioassay-tested and ships with a Certificate of Analysis. Standardize your organoid protocol once and reproduce it lot after lot.
Endotoxin-free from the source
Barley-produced, not bacterial or animal-derived: <0.01 EU/µg endotoxin with low pyrogenic activity, so your organoid data reflects biology, not reagents.
Animal-free, fully defined
Animal- and serum-free, void of antibiotics, with native eukaryotic folding for high bioactivity in defined-condition organoid media.
ISOkine® Premium
The factors organoid protocols rely on
Epithelial growth factors
KGF/FGF-7 drives epithelial proliferation for intestinal and other epithelial organoids, alongside EGF and FGF-2 for core proliferation.
See the ISOkine® range
BMP inhibition with Noggin
Noggin supports organoid maintenance through BMP inhibition, a staple of many organoid media formulations.
Documented, animal-free supply
Datasheets, Certificates of Analysis, Safety Data Sheets, and Certificates of Origin for every factor. ISO 9001:2015 certified, produced on the 25-year Orfeus barley platform.
Explore the technologyFrom model to supply, in three steps
Getting started
Match factors to your organoid model
Tell us your organoid type and media requirements. Browse the ISOkine® catalog or talk to a scientist for the right factors.
Request a quote or sample
Quote-based ordering, no account needed. Datasheets and CoA are available for every factor.
Reproduce with consistent supply
Lot-tested quality holds across your project, so an established organoid protocol stays reproducible.
Questions from organoid teams
Answers to the questions organoid researchers ask most about ISOkine® growth factors.
KGF/FGF-7 for epithelial proliferation and Noggin for BMP inhibition are the core organoid factors, supported by EGF and FGF-2. All are available animal-free and endotoxin-free.
Each ISOkine® lot is tested in a cell-based proliferation assay and ships with bioactivity data and a Certificate of Analysis, so potency is consistent from lot to lot.
Yes. Datasheets, Certificates of Analysis, Safety Data Sheets, and Certificates of Origin are available for every ISOkine® factor.
Get started
Keep your organoid models reproducible
Talk to our scientists about your application or request a quote. ISO 9001 certified, worldwide distribution, datasheets available on request.
Quote-based ordering. Datasheets and CoA available on request. Worldwide distribution.